LncRNA structure: message to the heart

Fazal FM, Chang HY.

Molecular Cell, 2016

doi:10.1016/j.molcel.2016.09.030

In this issue, Xue et al. (2016) describe the secondary structure of the heart-specific long non-coding RNA Braveheart, leading to the discovery of a short, asymmetric G-rich loop that controls cardiac lineage commitment by interacting with the transcription factor CNBP.